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1

Topoisomerase I inhibitors: camptothecins and beyond

Journal:

Nature Reviews Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 591 KB

english, 2006

2

SPIE Proceedings [SPIE Photonics Europe - Strasbourg, France (Monday 3 April 2006)] Optical Micro- and Nanometrology in Microsystems Technology - Continuous writing technique of long gratings for metrological applications

Gamet, Emilie, Gorecki, Christophe, Asundi, Anand K., Jourlin, Yves, Reynaud, Stéphanie, Osten, Wolfgang, Pommier, Jean-Claude, Parriaux, Olivier

Année:

2006

Langue:

english

Fichier:

PDF, 327 KB

english, 2006

3

Detection of apoptosis-associated DNA fragmentation using a rapid and quantitative filter elution assay

Richard Bertrand, Kurt W. Kohn, Eric Solary, Yves Pommier

Journal:

Drug Development Research

Année:

1995

Langue:

english

Fichier:

PDF, 594 KB

english, 1995

4

Integrase inhibitors to treat HIV/Aids

Pommier, Yves, Johnson, Allison A., Marchand, Christophe

Journal:

Nature Reviews Drug Discovery

Année:

2005

Langue:

english

Fichier:

PDF, 535 KB

english, 2005

5

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

Yves Pommier, Philippe Pourquier, Yi Fan, Dirk Strumberg

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Année:

1998

Langue:

english

Fichier:

PDF, 621 KB

english, 1998

6

Induction of a Common Pathway of Apoptosis by Staurosporine

Richard Bertrand, Eric Solary, Patrick O'Connor, Kurt W. Kohn, Yves Pommier

Journal:

Experimental Cell Research

Année:

1994

Fichier:

PDF, 737 KB

1994

7

Inhibition of human immunodeficiency virus type-1 integrase by curcumin

Abhijit Mazumder, Krishnamachari Raghavan, John Weinstein, Kurt W. Kohn, Yves Pommier

Journal:

Biochemical Pharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 731 KB

english, 1995

8

Drugging Topoisomerases: Lessons and Challenges

Journal:

ACS Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 3.66 MB

english, 2013

9

Curcumin Analogs with Altered Potencies against HIV-1 Integrase as Probes for Biochemical Mechanisms of Drug Action

Mazumder, Abhijit, Neamati, Nouri, Sunder, Sanjay, Schulz, Jutta, Pertz, Heinz, Eich, Eckart, Pommier, Yves

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 209 KB

english, 1997

10

Resistance to Integrase Inhibitors

Métifiot, Mathieu, Marchand, Christophe, Maddali, Kasthuraiah, Pommier, Yves

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2010

11

Design, Synthesis, and Biological Evaluation of 14-Substituted Aromathecins as Topoisomerase I Inhibitors

Cinelli, Maris A., Morrell, Andrew, Dexheimer, Thomas S., Scher, Evan S., Pommier, Yves, Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 586 KB

english, 2008

12

Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2 H )-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors

Patel, Maulik R., Bhatt, Aaditya, Steffen, Jamin D., Chergui, Adel, Murai, Junko, Pommier, Yves, Pascal, John M., Trombetta, Louis D., Fronczek, Frank R., Talele, Tanaji T.

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 5.58 MB

english, 2014

13

Hydrazide-Containing Inhibitors of HIV-1 Integrase †

Zhao, He, Neamati, Nouri, Sunder, Sanjay, Hong, Huixiao, Wang, Shaomeng, Milne, George W. A., Pommier, Yves, Burke, Terrence R.

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 180 KB

english, 1997

14

Discovery of Potent Indenoisoquinoline Topoisomerase I Poisons Lacking the 3-Nitro Toxicophore

Beck, Daniel E., Abdelmalak, Monica, Lv, Wei, Reddy, P. V. Narasimha, Tender, Gabrielle S., O’Neill, Elizaveta, Agama, Keli, Marchand, Christophe, Pommier, Yves, Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 789 KB

english, 2015

15

Cycle cellulaire et points de contrôle en oncologie : nouvelles cibles thérapeutiques

Pommier, Yves, Kohn, Kurt W.

Journal:

médecine/sciences

Année:

2003

Langue:

french

Fichier:

PDF, 311 KB

french, 2003

16

Temozolomide in the Era of Precision Medicine

Thomas, Anish, Tanaka, Mamoru, Trepel, Jane, Reinhold, William C., Rajapakse, Vinodh N., Pommier, Yves

Journal:

Cancer Research

Année:

2017

Langue:

english

Fichier:

PDF, 295 KB

english, 2017

17

Long-Term Real-Life Efficacy and Safety of Repeated Ozurdex® Injections and Factors Associated with Macular Edema Resolution after Retinal Vein Occlusion: The REMIDO 2 Study

Pommier, Stéphan, Meyer, Franck, Guigou, Sébastien, Barthelemy, Tony, Gobert, Fréderic, Hajjar, Christian, Merite, Pierre-Yves, Parrat, Eric, Rouhette, Hervé, Matonti, Fréderic

Journal:

Ophthalmologica

Année:

2016

Langue:

english

Fichier:

PDF, 151 KB

english, 2016

18

Characterization and structure-activity relationships of indenoisoquinoline-derived topoisomerase I inhibitors in unsilencing the dormant Ube3a gene associated with Angelman syndrome

Lee, Hyeong-Min, Clark, Ellen P., Kuijer, M. Bram, Cushman, Mark, Pommier, Yves, Philpot, Benjamin D.

Journal:

Molecular Autism

Année:

2018

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2018

19

PARP Trapping Beyond Homologous Recombination and Platinum Sensitivity in Cancers

Murai, Junko, Pommier, Yves

Journal:

Annual Review of Cancer Biology

Année:

2019

Langue:

english

Fichier:

PDF, 967 KB

english, 2019

20

Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[ c ]pyrrolo[2,3- h ][1,6]naphthyridin-5-one (BPN) Series

Elsayed, Mohamed S. A., Nielsen, Jeffery J., Park, Sungtae, Park, Jeongho, Liu, Qingyang, Kim, Chang H., Pommier, Yves, Agama, Keli, Low, Philip S., Cushman, Mark

Journal:

Journal of Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 7.91 MB

english, 2018

21

Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI anticancer drug screen: Multifactorial relationships with topoisomerase i, protein kinase C, Bcl-2, p53, MDM-2 and caspase pathways

Wilberto Nieves-Neira, Yves Pommier

Journal:

International Journal of Cancer

Année:

1999

Langue:

english

Fichier:

PDF, 263 KB

english, 1999

22

ChemInform Abstract: Synthesis of Cytotoxic Indenoisoquinoline Topoisomerase I Poisons.

Dirk Strumberg, Yves Pommier, Kenneth Paull, Muthusamy Jayaraman, Pamela Nagafuji, Mark Cushman

Journal:

Année:

1999

Fichier:

PDF, 30 KB

1999

23

ChemInform Abstract: Synthesis of New Indeno[1,2-c]isoquinolines: Cytotoxic Non-Camptothecin Topoisomerase I Inhibitors.

Mark Cushman, Muthusamy Jayaraman, Jeffrey A. Vroman, Anna K. Fukunaga, Brian M. Fox, Glenda Kohlhagen, Dirk Strumberg, Yves Pommier

Journal:

Année:

2001

Fichier:

PDF, 34 KB

2001

24

ChemInform Abstract: Discovery of a Nuclease-Resistant, Non-natural Dinucleotide that Inhibits HIV-1 Integrase.

Michael Taktakishvili, Nouri Neamati, Yves Pommier, Vasu Nair

Journal:

Année:

2001

Fichier:

PDF, 25 KB

2001

25

ChemInform Abstract: Synthesis of New Dihydroindeno[1,2-c]isoquinoline and Indenoisoquinolinium Chloride Topoisomerase I Inhibitors Having High in vivo Anticancer Activity in the Hollow Fiber Animal Model.

Muthusamy Jayaraman, Brian M. Fox, Melinda Hollingshead, Glenda Kohlhagen, Yves Pommier, Mark Cushman

Journal:

Année:

2002

Fichier:

PDF, 41 KB

2002

26

Azido-Containing Aryl β-Diketo Acid HIV-1 Integrase Inhibitors.

Xuechun Zhang, Godwin C. G. Pais, Evguenia S. Svarovskaia, Christophe Marchand, Allison A. Johnson, Rajeshri G. Karki, Marc C. Nicklaus, Vinay K. Pathak, Yves Pommier, Terrence R. Jr. Burke

Journal:

Année:

2003

Fichier:

PDF, 72 KB

2003

27

Structural Basis for Topoisomerase I Inhibition by Nucleoside Analogues

William H. Gmeiner, Shuyuan Yu, Richard T. Pon, Philippe Pourquier, Yves Pommier

Journal:

Année:

2004

Fichier:

PDF, 70 KB

2004

28

Design and Synthesis of Photoactivatable Aryl Diketo Acid-Containing HIV-1 Integrase Inhibitors (I) as Potential Affinity Probes.

Xuechun Zhang, Christophe Marchand, Yves Pommier, Terrence R. Jr. Burke

Journal:

Année:

2004

Fichier:

PDF, 62 KB

2004

29

Synthesis of Nitrated Indenoisoquinolines as Topoisomerase I Inhibitors.

Andrew Morrell, Smitha Antony, Glenda Kohlhagen, Yves Pommier, Mark Cushman

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 21 KB

english, 2004

30

ChemInform Abstract: DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

Journal:

Année:

2009

Fichier:

PDF, 15 KB

2009

31

ABCG2 overexpression in colon cancer cells resistant to SN38 and in irinotecan-treated metastases

Laurent Candeil, Isabelle Gourdier, Delphine Peyron, Nadia Vezzio, Virginie Copois, Frederic Bibeau, Beatrice Orsetti, George L. Scheffer, Marc Ychou, Qasim A. Khan, Yves Pommier, Bernard Pau, Pierre

Journal:

International Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 140 KB

english, 2004

32

Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells

Lancelot McLean, Ubaldo Soto, Keli Agama, Jawad Francis, Randi Jimenez, Yves Pommier, Lawrence Sowers, Eileen Brantley

Journal:

International Journal of Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 409 KB

english, 2008

33

Hydroxyrubicin, a deaminated derivative of doxorubicin, inhibits mammalian DNA topoisomerase II and partially circumvents multidrug resistance

Eric Solary, Vi-He Ling, Roman Perez-Soler, Waldemar Priebe, Yves Pommier

Journal:

International Journal of Cancer

Année:

1994

Langue:

english

Fichier:

PDF, 988 KB

english, 1994

34

Cellular pharmacology of azatoxins (topoisomerase-II and tubulin inhibitors) in P-glycoprotein-positive and -negative cell lines

Beatrice Eymin, Eric Solary, Sylvie Chevillard, Laurence Dubrez, François Goldwasser, Olivier Duchamp, Philippe Genne, François Leteurtre, Yves Pommier

Journal:

International Journal of Cancer

Année:

1995

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1995

35

High-order extended finite element method for cracked domains

Patrick Laborde, Julien Pommier, Yves Renard, Michel Salaün

Journal:

International Journal for Numerical Methods in Engineering

Année:

2005

Langue:

english

Fichier:

PDF, 585 KB

english, 2005

36

eXtended finite element methods for thin cracked plates with Kirchhoff–Love theory

Jérémie Lasry, Julien Pommier, Yves Renard, Michel Salaün

Journal:

International Journal for Numerical Methods in Engineering

Année:

2010

Langue:

english

Fichier:

PDF, 754 KB

english, 2010

37

DNA Interaction and Topoisomerase II Inhibition by the Antitumor Agent 3′-(9-Acridinylamino)-5′-hydroxymethylaniline and Derivatives

Alex Scarborough, Tsann-Long Su, F.F. Leteutre, Yves Pommier, Ting-Chao Chou

Journal:

Bioorganic Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 229 KB

english, 1996

38

Hybrid discretization of the Signorini problem with Coulomb friction. Theoretical aspects and comparison of some numerical solvers

Houari Boumediène Khenous, Julien Pommier, Yves Renard

Journal:

Applied Numerical Mathematics

Année:

2006

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2006

39

Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies

Gary S. Laco, Wu Du, Glenda Kohlhagen, Jane M. Sayer, Donald M. Jerina, Thomas G. Burke, Dennis P. Curran, Yves Pommier

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 597 KB

english, 2004

40

Design, synthesis, and biological evaluation of cytotoxic 11-aminoalkenylindenoisoquinoline and 11-diaminoalkenylindenoisoquinoline topoisomerase I inhibitors

Xiangshu Xiao, Smitha Antony, Glenda Kohlhagen, Yves Pommier, Mark Cushman

Journal:

Bioorganic & Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 576 KB

english, 2004

41

Mining the NCI antiviral compounds for HIV-1 integrase inhibitors

Jinxia Deng, James A. Kelley, Joseph J. Barchi, Tino Sanchez, Raveendra Dayam, Yves Pommier, Nouri Neamati

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 519 KB

english, 2006

42

A novel diketo phosphonic acid that exhibits specific, strand-transfer inhibition of HIV integrase and anti-HIV activity

Guochen Chi, Vasu Nair, Elena Semenova, Yves Pommier

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 137 KB

english, 2007

43

Regiocontrolled synthesis and HIV inhibitory activity of unsymmetrical binaphthoquinone and trimeric naphthoquinone derivatives of conocurvone

Kenneth W. Stagliano, Ashkan Emadi, Zhenhai Lu, Helena C. Malinakova, Barry Twenter, Min Yu, Louis E. Holland, Amanda M. Rom, John S. Harwood, Ronak Amin, Allison A. Johnson, Yves Pommier

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 319 KB

english, 2006

44

Synthesis and biological assays of E-ring analogs of camptothecin and homocamptothecin

Raghuram S. Tangirala, Smitha Antony, Keli Agama, Yves Pommier, Bradley D. Anderson, Robert Bevins, Dennis P. Curran

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 331 KB

english, 2006

45

Biotinylated biphenyl ketone-containing 2,4-dioxobutanoic acids designed as HIV-1 integrase photoaffinity ligands

Xue Zhi Zhao, Elena A. Semenova, Chenzhong Liao, Marc Nicklaus, Yves Pommier, Terrence R. Burke Jr.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 706 KB

english, 2006

46

Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: Investigating the hypothesis of shared structure–activity relationships

Maris A. Cinelli, Brenda Cordero, Thomas S. Dexheimer, Yves Pommier, Mark Cushman

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 732 KB

english, 2009

47

Corrigendum to “Inhibitors of human tyrosyl-DNA phospodiesterase (hTdp1) developed by virtual screening using ligand-based pharmacophores” [Bioorg. Med. Chem. 18 (2010) 182–189]

Iwona E. Weidlich, Thomas Dexheimer, Christophe Marchand, Smitha Antony, Yves Pommier, Marc C. Nicklaus

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 91 KB

english, 2010

48

Peptidic HIV integrase inhibitors derived from HIV gene products: Structure–activity relationship studies

Shintaro Suzuki, Kasthuraiah Maddali, Chie Hashimoto, Emiko Urano, Nami Ohashi, Tomohiro Tanaka, Taro Ozaki, Hiroshi Arai, Hiroshi Tsutsumi, Tetsuo Narumi, Wataru Nomura, Naoki Yamamoto, Yves Pommier,

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 713 KB

english, 2010

49

Design and synthesis of photoactivatable aryl diketo acid-containing HIV-1 integrase inhibitors as potential affinity probes

Xuechun Zhang, Christophe Marchand, Yves Pommier, Terrence R. Burke Jr.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 133 KB

english, 2004

50

Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors

Andrew Morrell, Smitha Antony, Glenda Kohlhagen, Yves Pommier, Mark Cushman

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 292 KB

english, 2004